The Peter Attia Drive Podcast
The Peter Attia Drive is a deep-dive podcast that explores the science and art of living the longest and healthiest life possible. With over 100 million downloads, The Peter Attia Drive investigates everything from exercise and nutritional biochemistry to cardiovascular health, cancer, cognitive health, mental and emotional well-being, and beyond. Each episode brings listeners closer to the cutting edge of what it means to thrive.
Women’s Sexual Health, Menopause, and Hormone Replacement Therapy- The Peter Attia Drive, Episode 348, with Rachel Rubin, MD
Rachel Rubin is a board-certified urologist and one of the nation’s foremost experts in sexual health. In this episode, she shares her deep expertise on the often-overlooked topic of women’s sexual health, exploring why this area remains so neglected in traditional medicine and highlighting the critical differences in how men and women experience hormonal decline with age. Rachel explains the physiology of the menstrual cycle, the complex hormonal shifts of perimenopause, and the wide-reaching health risks associated with menopause, including osteoporosis, cardiovascular disease, dementia, and recurrent urinary tract infections. She also breaks down the controversy surrounding hormone replacement therapy (HRT), particularly the damaging legacy of the Women’s Health Initiative study, and provides guidance on the safe and personalized use of estrogen, progesterone, and testosterone in women. With particular emphasis on local vaginal hormone therapy—a safe, effective, and underused treatment—Rachel offers insights that have the potential to transform quality of life for countless women.